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Molecular Diagnostics

Molecular Diagnostics

Author: Lela Buckingham
Publisher: F.A. Davis
ISBN: 0803629753
Pages: 576
Year: 2011-12-13
This exceptional resource introduces the fundamentals of nucleic acid biochemistry as well as the advanced concepts integral to professional practice in today's laboratories. With a focus on the application of molecular concepts to diagnose diseases, the 2nd Edition reflects the many advances in this rapidly developing field. Inside, you’ll find in-depth explanations of the principles of molecular-based assays as well as reference material and trouble-shooting tips for the laboratory. Discussions of general diagnostic procedures reflect the continuing emergence of new diagnostic technologies to prepare you to meet the challenges of the future.
Fundamentals of Molecular Diagnostics

Fundamentals of Molecular Diagnostics

Author: David E. Bruns, Edward R. Ashwood, Carl A. Burtis
Publisher: Elsevier Health Sciences
ISBN: 1416037373
Pages: 267
Year: 2007
This book offers an introduction to the newest, fastest-growing field in laboratory science. Explaining and clarifying the molecular techniques used in diagnostic testing, this text provides both entry-level and advanced information. It covers the principles of molecular biology along with genomes and nucleic acid alterations, techniques and instrumentation, and applications of molecular diagnostics. Written by leading experts, including Patrick Bossuyt, Angela Caliendo, Rossa W.K. Chiu, Kojo S.J. Elenitoba-Johnson, Andrea Ferreira-Gonzalez, Amy Groszbach, Sultan Habeebu, Doris Haverstick, Malek Kamoun, Anthony Killeen, Noriko Kusukawa, Y.M. Dennis Lo, Elaine Lyon, Gwendolyn McMillin, Christopher Price, James Versalovic, Cindy Vnencak-Jones, Victor Weedn, Peter Wilding, Thomas Williams, and Carl Wittwer, this book includes illustrations, tables, and a colorful design to make information easy to find and easy to use. A full-color, 4-page insert shows realistic images of the output for many molecular tests. Learning Objectives open each chapter with an overview of what you should achieve. Key Words are listed and defined at the beginning of each chapter, and are bolded in the text. Review Questions at the end of every chapter let you measure your comprehension. Advanced Concepts are included, but set apart from the rest of the text, for students who want a higher level of learning. Ethics boxes address ethical issues, allowing you to apply your knowledge to real-life scenarios. A glossary of all key words may be easily accessed in the back of the book.
Molecular Diagnostics

Molecular Diagnostics

Author: Wayne W. Grody, Robert M. Nakamura, Frederick L. Kiechle, Charles Strom
Publisher: Academic Press
ISBN: 0080919049
Pages: 736
Year: 2009-11-06
Advances in genomic and proteomic profiling of disease have transformed the field of molecular diagnostics, thus leading the way for a major revolution in clinical practice. While the range of tests for disease detection and staging is rapidly expanding, many physicians lack the knowledge required to determine which tests to order and how to interpret results. Molecular Diagnostics provides a complete guide to the use and interpretation of molecular testing in the clinical arena. No other available resource offers this emphasis, comprehensive scope, and practical utility in the clinical setting. Serves as the definitivereference for molecular pathologists worldwide Covers a variety of molecular techniques including next generation sequencing, tumor somatic cell genotyping, infectious and genetic disease tecting, and pharmacogenetics Discusses in the detail issues concerning quality assurance, regulation, ethics, and future directions for the science
Molecular Diagnostics, Fundamentals, Methods, and Clinical Applications

Molecular Diagnostics, Fundamentals, Methods, and Clinical Applications

Author: CTI Reviews
Publisher: Cram101 Textbook Reviews
ISBN: 1467289159
Pages: 86
Year: 2016-10-16
Facts101 is your complete guide to Molecular Diagnostics, Fundamentals, Methods, and Clinical Applications. In this book, you will learn topics such as as those in your book plus much more. With key features such as key terms, people and places, Facts101 gives you all the information you need to prepare for your next exam. Our practice tests are specific to the textbook and we have designed tools to make the most of your limited study time.
Tietz Textbook of Clinical Chemistry and Molecular Diagnostics - E-Book

Tietz Textbook of Clinical Chemistry and Molecular Diagnostics - E-Book

Author: Carl A. Burtis, Edward R. Ashwood, David E. Bruns
Publisher: Elsevier Health Sciences
ISBN: 1455759422
Pages: 2256
Year: 2012-10-14
As the definitive reference for clinical chemistry, Tietz Textbook of Clinical Chemistry and Molecular Diagnostics, 5th Edition offers the most current and authoritative guidance on selecting, performing, and evaluating results of new and established laboratory tests. Up-to-date encyclopedic coverage details everything you need to know, including: analytical criteria for the medical usefulness of laboratory procedures; new approaches for establishing reference ranges; variables that affect tests and results; the impact of modern analytical tools on lab management and costs; and applications of statistical methods. In addition to updated content throughout, this two-color edition also features a new chapter on hemostasis and the latest advances in molecular diagnostics. Section on Molecular Diagnostics and Genetics contains nine expanded chapters that focus on emerging issues and techniques, written by experts in field, including Y.M. Dennis Lo, Rossa W.K. Chiu, Carl Wittwer, Noriko Kusukawa, Cindy Vnencak-Jones, Thomas Williams, Victor Weedn, Malek Kamoun, Howard Baum, Angela Caliendo, Aaron Bossler, Gwendolyn McMillin, and Kojo S.J. Elenitoba-Johnson. Highly-respected author team includes three editors who are well known in the clinical chemistry world. Reference values in the appendix give you one location for comparing and evaluating test results. NEW! Two-color design throughout highlights important features, illustrations, and content for a quick reference. NEW! Chapter on hemostasis provides you with all the information you need to accurately conduct this type of clinical testing. NEW! Six associate editors, Ann Gronowski, W. Greg Miller, Michael Oellerich, Francois Rousseau, Mitchell Scott, and Karl Voelkerding, lend even more expertise and insight to the reference. NEW! Reorganized chapters ensure that only the most current information is included.
Molecular Diagnostics

Molecular Diagnostics

Author: Gregory J. Tsongalis, William B. Coleman
Publisher: Amer. Assoc. for Clinical Chemistry
ISBN: 189088376X
Pages: 364
Year: 2002-01-01

Molecular Pathology

Molecular Pathology

Author: William B. Coleman, Gregory J. Tsongalis
Publisher: Academic Press
ISBN: 0128027878
Pages: 802
Year: 2017-11-09
As the molecular basis of human disease becomes better characterized, and the implications for understanding the molecular basis of disease becomes realized through improved diagnostics and treatment, Molecular Pathology, Second Edition stands out as the most comprehensive textbook where molecular mechanisms represent the focus. It is uniquely concerned with the molecular basis of major human diseases and disease processes, presented in the context of traditional pathology, with implications for translational molecular medicine. The Second Edition of Molecular Pathology has been thoroughly updated to reflect seven years of exponential changes in the fields of genetics, molecular, and cell biology which molecular pathology translates in the practice of molecular medicine. The textbook is intended to serve as a multi-use textbook that would be appropriate as a classroom teaching tool for biomedical graduate students, medical students, allied health students, and others (such as advanced undergraduates). Further, this textbook will be valuable for pathology residents and other postdoctoral fellows that desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. In addition, this textbook is useful as a reference book for practicing basic scientists and physician scientists that perform disease-related basic science and translational research, who require a ready information resource on the molecular basis of various human diseases and disease states. Explores the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease Explains the practice of “molecular medicine and the translational aspects of molecular pathology Teaches from the perspective of “integrative systems biology Enhanced digital version included with purchase

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ISBN: 0323548482
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Fundamental Laboratory Mathematics

Fundamental Laboratory Mathematics

Author: Lela Buckingham
Publisher: F.A. Davis
ISBN: 0803641028
Pages: 350
Year: 2014-05-16
Conquer the math skills essential for the laboratory... and reduce the anxieties math often induces! Step by step, skill by skill... you’ll progress from simple to complex calculations, building your proficiencies and testing them along the way. Perfect for classroom, clinical, and professional success!
Next Generation Sequencing

Next Generation Sequencing

Author: Lee-Jun C. Wong
Publisher: Springer Science & Business Media
ISBN: 1461470013
Pages: 302
Year: 2013-05-31
In recent years, owing to the fast development of a variety of sequencing technologies in the post human genome project era, sequencing analysis of a group of target genes, entire protein coding regions of the human genome, and the whole human genome has become a reality. Next Generation Sequencing (NGS) or Massively Parallel Sequencing (MPS) technologies offers a way to screen for mutations in many different genes in a cost and time efficient manner by deep coverage of the target sequences. This novel technology has now been applied to clinical diagnosis of Mendelian disorders of well characterized or undefined diseases, discovery of new disease genes, noninvasive prenatal diagnosis using maternal blood, and population based carrier testing of severe autosomal recessive disorders. This book covers topics of these applications, including potential limitations and expanded application in the future. ​
Diagnostic Molecular Pathology in Practice

Diagnostic Molecular Pathology in Practice

Author: Iris Schrijver
Publisher: Springer Science & Business Media
ISBN: 3642196772
Pages: 339
Year: 2011-09-09
This entirely case-based book covers a broad cross-section of the practical issues frequently encountered in the day-to-day activities of a molecular genetic pathologist. The book is divided into four sections on the principal areas addressed in molecular genetic pathology (MGP): inherited diseases, hematopathology, solid tumors, and infectious diseases. The topics covered by the cases in each section include test selection, qualitative and quantitative laboratory techniques, test interpretation, prognostic and therapeutic considerations, ethical considerations, technical troubleshooting, and result reporting. This book will be ideal for trainees in MGP and clinical molecular genetics who require a practice-based preparation for board examinations. It will also be very useful for residents and fellows in medical specialties to which MGP is pertinent, and for practicing pathologists who want to learn more about the current practice of molecular diagnostics.
Molecular Diagnostics

Molecular Diagnostics

Author: George P. Patrinos, Wilhelm Ansorge, Phillip B. Danielson
Publisher: Academic Press
ISBN: 0128029889
Pages: 520
Year: 2016-10-27
Molecular Diagnostics, Third Edition, focuses on the technologies and applications that professionals need to work in, develop, and manage a clinical diagnostic laboratory. Each chapter contains an expert introduction to each subject that is next to technical details and many applications for molecular genetic testing that can be found in comprehensive reference lists at the end of each chapter. Contents are divided into three parts, technologies, application of those technologies, and related issues. The first part is dedicated to the battery of the most widely used molecular pathology techniques. New chapters have been added, including the various new technologies involved in next-generation sequencing (mutation detection, gene expression, etc.), mass spectrometry, and protein-specific methodologies. All revised chapters have been completely updated, to include not only technology innovations, but also novel diagnostic applications. As with previous editions, each of the chapters in this section includes a brief description of the technique followed by examples from the area of expertise from the selected contributor. The second part of the book attempts to integrate previously analyzed technologies into the different aspects of molecular diagnostics, such as identification of genetically modified organisms, stem cells, pharmacogenomics, modern forensic science, molecular microbiology, and genetic diagnosis. Part three focuses on various everyday issues in a diagnostic laboratory, from genetic counseling and related ethical and psychological issues, to safety and quality management. Presents a comprehensive account of all new technologies and applications used in clinical diagnostic laboratories Explores a wide range of molecular-based tests that are available to assess DNA variation and changes in gene expression Offers clear translational presentations by the top molecular pathologists, clinical chemists, and molecular geneticists in the field
Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics - E-Book

Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics - E-Book

Author: Carl A. Burtis, David E. Bruns
Publisher: Elsevier Health Sciences
ISBN: 0323292062
Pages: 1104
Year: 2014-08-14
A condensed, easier-to-understand student version of the acclaimed Tietz Textbook of Clinical Chemistry and Molecular Diagnostics, Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics, 7th Edition uses a laboratory perspective in providing the clinical chemistry fundamentals you need to work in a real-world, clinical lab. Coverage ranges from laboratory principles to analytical techniques and instrumentation, analytes, pathophysiology, and more. New content keeps you current with the latest developments in molecular diagnostics. From highly respected clinical chemistry experts Carl Burtis and David Bruns, this textbook shows how to select and perform diagnostic lab tests, and accurately evaluate results. Authoritative, respected author team consists of two well-known experts in the clinical chemistry world. Coverage of analytical techniques and instrumentation includes optical techniques, electrochemistry, electrophoresis, chromatography, mass spectrometry, enzymology, immunochemical techniques, microchips, automation, and point of care testing. Learning objectives begin each chapter, providing measurable outcomes to achieve after completing the material. Key words are listed and defined at the beginning of each chapter, and bolded in the text. A glossary at the end of the book makes it quick and easy to look up definitions of key terms. More than 500 illustrations plus easy-to-read tables help you understand and remember key concepts. New chapters on molecular diagnostics include the principles of molecular biology, nucleic acid techniques and applications, and genomes and nucleic acid alterations, reflecting the changes in this rapidly evolving field. New content on clinical evaluation of methods, kidney function tests, and diabetes is added to this edition. NEW multiple-choice review questions at the end of each chapter allow you to measure your comprehension of the material. NEW case studies on the Evolve companion website use real-life scenarios to reinforce concepts.
Diagnostic Molecular Pathology

Diagnostic Molecular Pathology

Author: Debra G. B. Leonard
Publisher: Saunders
ISBN: 0721600476
Pages: 208
Year: 2003
This practical guide provides information essential to understanding the significance of molecular biology and its application to everyday practice. Coverage focuses on the spectrum of currently used molecular tests in the areas of hematopathology, solid tumors, genetics, and identify testing. Examples of both molecular and cytogenetic assays demonstrate how these tests are used in today's pathology labs to detect a wide range of infectious diseases and inherited and metabolic conditions. Presents the full range of molecular diagnostic methods from the standpoint of their clinical applications and diagnostic value. Provides full-chapter coverage of each type of molecular testing, including genetics · carcinomas · sarcomas · leukemias and lymphomas · and identity testing. Concisely covers all areas of molecular pathology-making it the single source for all aspects of this field. Features the contributions of 12 leading experts in molecular pathology. Offers a complete introduction to molecular biology as well as common molecular methods of testing. Focuses on test utility as well as test interpretation and significance. With 11 additional contributors.
Clinical Laboratory Immunology

Clinical Laboratory Immunology

Author: Connie R. Mahon, Diane G. Tice
Publisher: Prentice Hall
ISBN: 0130933007
Pages: 325
Year: 2006
This unique resource is the first covering molecular diagnostic technology that is specifically geared to the needs of those in clinical laboratory sciene or medical technology. This book covers molecular diagnostic technology and the multidisciplinary clinical applications of this technology. Topics include: immunology; infectious and autoimmune diseases; clinical applications of the flow of cytometry; organ transplantation; molecular methods and more. Clinical Laboratory Science / Medical Technology students.